After publishing the first article concerning Mathew Perry’s death, The Epoch Times newspaper health writer Marina Zhang contacted me about expounding on the details surrounding some of the unanswered questions. The article posted on their website:
I read the Epoch Times article and here’s my take:
I agree with these statements, but in other ways, I can’t entirely agree. Certainly, it’s possible the level of dissociative anesthesia was sufficient to render Perry unable to respond to the lack of oxygen while underwater. However, to play devil’s advocate, when we are exposed to profound hypoxemia, as would have had to occur drowning in a shallow jacuzzi, humans have what’s called a “hypoxia reflex.” The body’s response to drowning begins when the brain senses hypoxia (oxygen deprivation). This causes the nervous system to trigger a series of reactions meant to protect vital organs, i.e., the brain, heart, and lungs, from damage until the person can breathe. This sympathetic reflex is so stimulating and violent that it would arouse just about anyone out of a stupor, including someone who has taken a lot of drugs. Part of the reason is the acute carbon dioxide increase resulting from decreased oxygen availability.
Perry would have likely inhaled some water and coughed violently, and his blood pressure and heart rate would have been through the roof, well and beyond any increase caused by the ketamine. I know; I’ve observed the effects of ketamine on the heart in the operating room for 20 years. Then Perry’s extensive reasons for having heart disease could have shown themselves, possibly developing a fatal arrhythmia such as pulseless ventricular tachycardia or fibrillation. Again, all speculation.
Ms. Zhang asked me about this possibility: Your substack post seemed to suggest that Perry likely died from a heart attack. Can you confirm your thoughts on what may have happened, considering the information from the coroner's report?
He was certainly a setup for a heart attack — pre-existing blockages in the left anterior descending coronary artery, COPD, mildly obese, just finished a high intensity exercise, a lot of ketamine and other drugs in his system, increased blood pressure and heart rate, and hypoxemia. Even though there was no evidence of a heart attack or ischemia in the autopsy, he easily could have suffered a lethal arrhythmia, which would not show up on autopsy. Here is a reference below from the BMC study:
“In a referred cohort of SUD cases, unspecific cardiac findings were seen in 63% of the autopsied with the most common findings including hypertrophy/enlargement of heart, coronary artery atheromatosis and diffuse fibrosis. These unspecific findings may be precursors or early signs of underlying structural cardiac disorders but could also be spur findings in patients with inherited arrhythmogenic disorders. In total, 37% of all victims had no cardiac finding on autopsy.”
At the end of the day, we will never know the answer to this question.